TrialEmulation - Causal Analysis of Observational Time-to-Event Data
Implements target trial emulation methods to apply randomized clinical trial design and analysis in an observational setting. Using marginal structural models, it can estimate intention-to-treat and per-protocol effects in emulated trials using electronic health records. A description and application of the method can be found in Danaei et al (2013) <doi:10.1177/0962280211403603>.
Last updated 7 days ago
causal-inferencelongitudinal-datasurvival-analysis
7.52 score 19 stars 24 scripts 261 downloads
maicplus - Matching Adjusted Indirect Comparison
Facilitates performing matching adjusted indirect comparison (MAIC) analysis where the endpoint of interest is either time-to-event (e.g. overall survival) or binary (e.g. objective tumor response). The method is described by Signorovitch et al (2012) <doi:10.1016/j.jval.2012.05.004>.
Last updated 12 hours ago
6.92 score 3 stars 6 scripts 196 downloadspsborrow - Bayesian Dynamic Borrowing with Propensity Score
A tool which aims to help evaluate the effect of external borrowing using an integrated approach described in Lewis et al., (2019) <doi:10.1080/19466315.2018.1497533> that combines propensity score and Bayesian dynamic borrowing methods.
Last updated 2 years ago
2.60 score 1 stars 4 scripts 307 downloads